Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IAPP | P10997 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.45 |
| ▸ | MPI | P34949 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896077 | 0.83 | CA2 (0.50) | POLBRAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL7889090 | 0.79 | ERN1 (0.46) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL7900411 | 0.76 | ERN1 (0.46) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL6871801 | 0.72 | ERN1 (0.60) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL308223 | 0.71 | ERN1 (0.65) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL1805984 | 0.69 | RXRA (0.54) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL1805981 | 0.69 | RXRA (0.54) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL20534909 | 0.68 | ERN1 (0.56) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL9251009 | 0.68 | IAPP (0.60) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL9745412 | 0.68 | IAPP (0.60) | ERN1POLBGAARAB9AIAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |