Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.45 |
| ▸ | PI4KA | P42356 | 5/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.42 |
| ▸ | MTOR | P42345 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789702 | 0.79 | PIK3CG (0.52) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL789701 | 0.79 | PIK3CG (0.73) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807275 | 0.78 | PIK3CG (0.63) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL10277093 | 0.74 | KDM4E (0.43) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL791169 | 0.71 | PIK3CG (0.47) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL789984 | 0.70 | PI4KA (0.47) | PIK3CGPI4KAPIK3CAMTORPIK3R1 | |
| SCHEMBL806789 | 0.70 | PIK3CD (0.50) | PIK3CGPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL807212 | 0.69 | PIK3CD (0.46) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL806785 | 0.69 | PIK3CG (0.49) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790455 | 0.69 | PIK3CA (0.41) | PIK3CGPI4KAPIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |