Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAD1 | O60671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806747 | 0.87 | MEN1 (0.42) | MAPTMEN1HTTKMT2AALDH1A1 | |
| SCHEMBL24511910 | 0.86 | MAPT (0.44) | MAPTMEN1HTTKMT2AALDH1A1 | |
| SCHEMBL789351 | 0.86 | MAPT (0.47) | LGMNMAPTMEN1HTTKMT2A | |
| SCHEMBL17637634 | 0.84 | LGMN (0.43) | LGMNMAPTMEN1HTTKMT2A | |
| SCHEMBL17548072 | 0.84 | LGMN (0.43) | LGMNMAPTMEN1HTTKMT2A | |
| SCHEMBL30748846 | 0.82 | ALDH1A1 (0.47) | LGMNMAPTMEN1HTTKMT2A | |
| SCHEMBL791178 | 0.82 | ALDH1A1 (0.47) | LGMNMAPTMEN1HTTKMT2A | |
| SCHEMBL30180211 | 0.79 | SUV39H2 (0.38) | MAPTHTTKDM4EMAPK1GRM2 | |
| SCHEMBL30180207 | 0.79 | SUV39H2 (0.38) | MAPTHTTKDM4EMAPK1GRM2 | |
| SCHEMBL24847183 | 0.79 | SUV39H2 (0.38) | MAPTHTTKDM4EMAPK1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |