Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180207 | 1.00 | SUV39H2 (0.38) | SUV39H2SYKWEE1ADRB1NOTUM | |
| SCHEMBL24847183 | 1.00 | SUV39H2 (0.38) | SUV39H2SYKWEE1ADRB1NOTUM | |
| SCHEMBL26447710 | 0.87 | MEN1 (0.35) | SUV39H2BRD4PTGESRORC | |
| SCHEMBL2053569 | 0.81 | LIPG (0.41) | RORC | |
| SCHEMBL806747 | 0.80 | MEN1 (0.42) | ADRB1HTTL3MBTL1MAPTMAPK1 | |
| SCHEMBL24511910 | 0.79 | MAPT (0.44) | HTTL3MBTL1MAPTMAPK1DRD2 | |
| SCHEMBL789720 | 0.79 | LGMN (0.44) | HTTL3MBTL1MAPTMAPK1LMNA | |
| SCHEMBL30180197 | 0.79 | LIPG (0.40) | SUV39H2BRD4RORC | |
| SCHEMBL24846896 | 0.79 | LIPG (0.40) | SUV39H2BRD4RORC | |
| SCHEMBL28978064 | 0.76 | L3MBTL1 (0.44) | SUV39H2SYKWEE1ADRB1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |