Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600104 | 0.86 | CCR2 (0.56) | CNR2NAMPTHRH3 | |
| SCHEMBL7887420 | 0.84 | HRH3 (0.56) | HRH3 | |
| SCHEMBL7893397 | 0.83 | L3MBTL3 (0.55) | HRH3 | |
| SCHEMBL7887253 | 0.80 | CHRNA7 (0.54) | HRH3 | |
| SCHEMBL7887462 | 0.78 | HRH3 (0.46) | HRH3 | |
| SCHEMBL7896454 | 0.78 | POLB (0.50) | HRH3 | |
| SCHEMBL13628510 | 0.77 | HRH3 (0.59) | HRH3 | |
| SCHEMBL13628044 | 0.77 | HRH3 (0.59) | HRH3 | |
| SCHEMBL7893524 | 0.76 | HRH3 (0.43) | HRH3 | |
| SCHEMBL25281317 | 0.75 | RAB9A (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086403-A1 | AZETIDINES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2010-08-05 | — | — | WO | disclosed |