Ether

Ether

SCHEMBL9252409

C=CC(=O)NC(O)C(=O)OCC.CCOCC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
ACACB O00763 2/20 0.36
ALDH1A1 P00352 4/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CAD P27708 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
METAP2 P50579 2/20 0.32
METAP1 P53582 1/20 0.32
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
TGM2 P21980 1/20 0.31
GSTO1 P78417 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7897232 0.95 TSHR (0.47) TSHRACACBALDH1A1MGAMGAA
Methoxymethane SCHEMBL9257609 0.91 TSHR (0.44) TSHRACACBALDH1A1MGAMGAA
Ether SCHEMBL9262685 0.90 TSHR (0.42) TSHRACACBALDH1A1ZDHHC20ZDHHC2
Ether SCHEMBL9640045 0.86 TSHR (0.47) TSHRACACBALDH1A1NPSR1ZDHHC20
SCHEMBL8326863 0.81 TSHR (0.44) TSHRACACBALDH1A1NPSR1ZDHHC20
SCHEMBL9316240 0.80 TSHR (0.40) TSHRACACBALDH1A1NPSR1ZDHHC20
SCHEMBL11038902 0.79 TSHR (0.50) TSHRACACBALDH1A1GAAZDHHC20
SCHEMBL10082440 0.78 TSHR (0.48) TSHRACACBALDH1A1MGAMGAA
SCHEMBL11118193 0.78 TSHR (0.46) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL7889412 0.78 TSHR (0.53) TSHRACACBALDH1A1NPSR1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4778869-A COATINGS, ADHESIVES, MOLDINGS AMERICAN CYANAMID COMPANY (US) 1988-10-18 US claimed
US-4656308-A COATINGS AMERICAN CYANAMID COMPANY (US) 1987-04-07 US claimed
EP-0049910-B1 COPOLYMERS FORMED FROM ACTIVATED ESTER MONOMERS, AND COATING COMPOSITIONS CONTAINING SAID COPOLYMERS AMERICAN CYANAMID COMPANY (US) 1986-02-19 EP claimed
US-4446280-A ALKYL ACRYLAMIDOGLYCOLATE ETHER POLYMER AMERICAN CYANAMID COMPANY (US) 1984-05-01 US claimed
EP-0020000-B1 ACTIVATED ESTER MONOMERS, POLYMERS FORMED THEREFROM AND COATING COMPOSITIONS CONTAINING SAID POLYMERS AMERICAN CYANAMID COMPANY (US) 1983-06-15 EP claimed
EP-0049910-A2 Copolymers formed from activated ester monomers, and coating compositions containing said copolymers AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP claimed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP claimed
US-5478688-A Liquid developer compositions with charge adjuvants of a copolymer of an alky acrylamidoglycolate alkyl ether and an alkenylester XEROX CORPORATION (US) 1995-12-26 US disclosed
US-5369204-A Low molecular weight acrylamidoglycolate crosslinker and process CYTEC TECHNOLOGY CORP. (US) 1994-11-29 US disclosed
WO-1993007186-A1 POLYMERS CONTAINING BETA-HYDROXYALKYLAMIDE GROUPS PPG INDUSTRIES, INC. (US) 1993-04-15 WO disclosed
US-5142019-A Oligomers formed from reaction of acrylamidoglycolate alkyl ethers with β-hydroxyalkylamines PPG INDUSTRIES, INC. (US) 1992-08-25 US disclosed
EP-0310808-B1 CURABLE COMPOSITIONS AND CORROSION RESISTANT COATINGS PREPARED THEREFROM AMERICAN CYANAMID COMPANY (US) 1992-08-05 EP disclosed
US-5116922-A Curable with no release of formaldehyde PPG INDUSTRIES, INC. (US) 1992-05-26 US disclosed
US-4528320-A Low temperature, moisture cure coating composition AMERICAN CYANAMID CO. (US) 1985-07-09 US disclosed
US-4522973-A POLYMER DERIVED FROM CERTAIN ACTIVATED ESTER CONTAINING VINYL MONOMER, PLUS CURING AGENT AMERICAN CYANAMID COMPANY (US) 1985-06-11 US disclosed
US-4521563-A ACRYLIC CARBOXYLATED AMIDE POLYMER AND AMINE/AMINAL CROSSLINKING MIXTURE AMERICAN CYANAMID COMPANY (US) 1985-06-04 US disclosed
EP-0138025-A1 Polyfunctional amine crosslinker, process for making same, and compositions containing same AMERICAN CYANAMID COMPANY (US) 1985-04-24 EP disclosed
EP-0020000-B1 ACTIVATED ESTER MONOMERS, POLYMERS FORMED THEREFROM AND COATING COMPOSITIONS CONTAINING SAID POLYMERS AMERICAN CYANAMID COMPANY (US) 1983-06-15 EP disclosed
EP-0049910-A2 Copolymers formed from activated ester monomers, and coating compositions containing said copolymers AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP disclosed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP disclosed