Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.35 |
| ▸ | FAAH | O00519 | 6/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16180595 | 0.68 | CA2 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27828979 | 0.63 | CA12 (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4937327 | 0.63 | CA2 (0.60) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL27821403 | 0.62 | GAA (0.35) | ALDH1A1LMNAMAPTHTTCA12 | |
| SCHEMBL1632277 | 0.62 | CA1 (0.63) | MGLLFAAHHSP90AA1ALDH1A1NPSR1 | |
| SCHEMBL10585998 | 0.61 | MGLL (0.57) | MGLLFAAHHSP90AA1G6PDTLR9 | |
| SCHEMBL29510588 | 0.60 | CA1 (0.62) | MGLLFAAHHSP90AA1ALDH1A1LMNA | |
| SCHEMBL28752515 | 0.60 | CA1 (0.62) | MGLLFAAHHSP90AA1ALDH1A1LMNA | |
| SCHEMBL20842649 | 0.59 | MGLL (0.48) | MGLLFAAHHSP90AA1G6PDTLR9 | |
| SCHEMBL3673619 | 0.58 | CA1 (0.30) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6190825-B1 | N-(P-AMINOSULFONYL)PHENYL-SUBSTITUTED | AGFA-GEVAERT N.V. (BE) | 2001-02-20 | — | — | US | disclosed |