Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193405 | 0.87 | L3MBTL1 (0.50) | L3MBTL1MAPK1MAPTALDH1A1TDP1 | |
| SCHEMBL391347 | 0.85 | KDM4E (0.55) | MAPK1MAPTALDH1A1TDP1TSHR | |
| SCHEMBL5191199 | 0.84 | L3MBTL1 (0.56) | L3MBTL1MAPK1ALDH1A1TDP1TSHR | |
| SCHEMBL11328532 | 0.83 | ALDH1A1 (0.52) | L3MBTL1MAPK1MAPTALDH1A1TDP1 | |
| SCHEMBL6198744 | 0.83 | ALDH1A1 (0.60) | MAPK1MAPTALDH1A1KDM4EMAOB | |
| SCHEMBL17560224 | 0.82 | L3MBTL1 (0.54) | L3MBTL1MAPK1ALDH1A1TDP1TSHR | |
| SCHEMBL27898281 | 0.81 | L3MBTL1 (0.66) | L3MBTL1MAPK1ALDH1A1TDP1TSHR | |
| SCHEMBL7888553 | 0.81 | L3MBTL1 (0.53) | L3MBTL1MAPK1ALDH1A1TDP1TSHR | |
| SCHEMBL1315571 | 0.80 | KDM4E (0.68) | L3MBTL1MAPK1MAPTALDH1A1TDP1 | |
| SCHEMBL17571992 | 0.80 | SMN1; SMN2 (0.56) | L3MBTL1MAPK1MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37035-E1 | HYPOGLYCEMIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-30 | — | — | US | disclosed |
| US-6143769-A | ENANTIOMORPH | KARL THOMAE GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| US-5312924-A | Compounds for lowering blood sugar and effecting metabolism | DR. KARL THOMAE GMBH (DE) | 1994-05-17 | — | — | US | disclosed |
| US-5216167-A | Hypoglycemic agents | DR. KARL THOMAE GMBH (DE) | 1993-06-01 | — | — | US | disclosed |