Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.44 |
| ▸ | FNTB | P49356 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907270 | 0.92 | FNTA (0.41) | FNTAFNTBTDP1PGGT1BGAA | |
| SCHEMBL7910059 | 0.85 | FNTA (0.60) | FNTAFNTBTDP1 | |
| SCHEMBL7910060 | 0.85 | FNTA (0.60) | FNTAFNTBTDP1 | |
| SCHEMBL7897673 | 0.80 | ALDH1A1 (0.43) | FNTAFNTBPPARGKCNA3BCL2L1 | |
| SCHEMBL7904342 | 0.78 | FNTA (0.39) | FNTAFNTBTDP1PGGT1B | |
| SCHEMBL6777951 | 0.78 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL6777949 | 0.78 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL6641648 | 0.76 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL4460274 | 0.75 | MAOB (0.57) | PPARGMAOBMAOARAB9A | |
| SCHEMBL6776059 | 0.75 | PDE4B (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |