Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906736 | 0.86 | FNTA (0.43) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7897668 | 0.78 | FNTA (0.44) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7907270 | 0.75 | FNTA (0.41) | FNTAFNTBPGGT1BKMT2ATDP1 | |
| SCHEMBL6775734 | 0.69 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL6777582 | 0.68 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL6778550 | 0.67 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7897673 | 0.67 | ALDH1A1 (0.43) | FNTAFNTBPGGT1BKMT2AMEN1 | |
| SCHEMBL7905106 | 0.66 | FNTA (0.64) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7905102 | 0.66 | FNTA (0.64) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL8194280 | 0.65 | FNTA (0.40) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | claimed |
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |