SCHEMBL7897682

SCHEMBL7897682

CC(C)(C)OC(=O)c1ccc(O)cc1OC(=O)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.69
ESR2 Q92731 3/20 0.69
SLC6A3 Q01959 1/20 0.49
ELANE P08246 1/20 0.45
MAPT P10636 6/20 0.43
KMT2A Q03164 5/20 0.43
TDP1 Q9NUW8 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 4/20 0.42
USP2 O75604 2/20 0.42
GAA P10253 2/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
JAK2 O60674 1/20 0.41
ALOX15 P16050 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615928 0.84 ESR1 (0.75) ESR1ESR2SLC6A3MAPTKMT2A
SCHEMBL7897674 0.83 SLC6A3 (0.55) ESR1ESR2SLC6A3ELANEMAPT
SCHEMBL5179548 0.82 ESR1 (1.00) ESR1ESR2SLC6A3MAPTKMT2A
SCHEMBL7769810 0.81 ESR1 (0.75) ESR1ESR2SLC6A3MAPTKMT2A
SCHEMBL6564075 0.81 ESR1 (0.69) ESR1ESR2SLC6A3MAPTKMT2A
SCHEMBL6564045 0.81 ESR1 (0.69) ESR1ESR2SLC6A3MAPTKMT2A
SCHEMBL27968816 0.79 EGFR (0.46) ESR1ESR2KMT2AALDH1A1TSHR
SCHEMBL7621537 0.78 ESR1 (0.66) ESR1ESR2SLC6A3ELANEMAPT
SCHEMBL6565963 0.78 ESR1 (0.69) ESR1ESR2SLC6A3MAPTKMT2A
SCHEMBL9496492 0.77 ESR1 (0.64) ESR1ESR2SLC6A3MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184300-B1 USEFUL AS HEAT-INSULATING MATERIAL, ORGANIC PIGMENT, OR OPACIFYING AGENT, AND AS HEAT-INSULATING INTERLAYER TO BE FORMED IN THERMAL RECORDING MATERIAL NIPPON ZEON CO., LTD. (JP) 2001-02-06 US disclosed
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP disclosed
US-5096873-A Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability JUJO PAPER CO., LTD. (JP) 1992-03-17 US disclosed
EP-0391434-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1990-10-10 EP disclosed
US-4918044-A LEUCO DYE, COLOR DEVELOPER, BIPHENYL TOLYL ETHER SENSITIZER, STABLE, HIGH DENSITY, HIGH SPEED RECORDING JUJO PAPER CO., LTD. (JP) 1990-04-17 US disclosed
EP-0289041-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-11-02 EP disclosed