SCHEMBL9496492

SCHEMBL9496492

CC(OC(=O)c1ccc(O)cc1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.64
ESR2 Q92731 3/20 0.64
SLC6A3 Q01959 1/20 0.46
HSD17B10 Q99714 2/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.45
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
OPRM1 P35372 3/20 0.41
KMT2A Q03164 4/20 0.40
MAPT P10636 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 3/20 0.40
HCAR2 Q8TDS4 1/20 0.40
USP2 O75604 2/20 0.39
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6564075 0.88 ESR1 (0.69) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL7894941 0.84 ESR1 (0.63) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL10727310 0.81 CA12 (0.67) ESR1ESR2HSD17B10ALDH1A1TP53
SCHEMBL7615928 0.81 ESR1 (0.75) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL8093516 0.79 ESR1 (0.68) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL5179548 0.79 ESR1 (1.00) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL7769810 0.78 ESR1 (0.75) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL6564045 0.77 ESR1 (0.69) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL7897682 0.77 ESR1 (0.69) ESR1ESR2SLC6A3HSD17B10ALDH1A1
SCHEMBL3628983 0.77 ESR1 (0.70) ESR1ESR2HSD17B10ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP disclosed
US-5096873-A Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability JUJO PAPER CO., LTD. (JP) 1992-03-17 US disclosed
EP-0391434-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1990-10-10 EP disclosed
US-4918044-A LEUCO DYE, COLOR DEVELOPER, BIPHENYL TOLYL ETHER SENSITIZER, STABLE, HIGH DENSITY, HIGH SPEED RECORDING JUJO PAPER CO., LTD. (JP) 1990-04-17 US disclosed
EP-0289041-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-11-02 EP disclosed