Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.52 |
| ▸ | ACLY | P53396 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955040 | 0.83 | PIK3CG (0.51) | LMNAPIK3CAACLYPIK3CDPIK3C3 | |
| SCHEMBL740363 | 0.81 | MEN1 (0.61) | LMNAPIK3CAACLYTHRBPIK3CD | |
| SCHEMBL16926674 | 0.77 | PIK3C3 (0.58) | PIK3CAPIK3C3 | |
| SCHEMBL25230896 | 0.74 | PIK3CA (0.56) | PIK3CAPIK3CDPIK3C3PIK3CBPI4KA | |
| SCHEMBL29536997 | 0.74 | PIK3CA (0.56) | PIK3CAPIK3CDPIK3C3PIK3CBPI4KA | |
| SCHEMBL9952995 | 0.73 | LMNA (0.49) | LMNAPIK3CAACLYTHRBPIK3CD | |
| SCHEMBL16990927 | 0.73 | PIK3C3 (0.81) | PIK3CAPIK3C3 | |
| SCHEMBL29463837 | 0.71 | LMNA (1.00) | LMNAPIK3CAACLYTHRBPIK3CD | |
| SCHEMBL18131006 | 0.71 | LMNA (1.00) | LMNAPIK3CAACLYTHRBPIK3CD | |
| SCHEMBL15870075 | 0.71 | ALOX5AP (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |