Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL28821631 | 0.96 | ACHE (0.44) | ACHEBACE1ERBB2MAOAMAOB | |
| SCHEMBL17388699 | 0.80 | STAT3 (0.38) | ERBB2TDP1MEN1MAPTKMT2A | |
| SCHEMBL28548919 | 0.78 | ACHE (0.53) | ACHEBACE1ERBB2MAOAMAOB | |
| SCHEMBL20087547 | 0.77 | MAOA (0.44) | ACHEBACE1ERBB2MAOAMAOB | |
| SCHEMBL9105522 | 0.77 | ERBB2 (0.34) | ERBB2 | |
| SCHEMBL9911033 | 0.77 | ERBB2 (0.34) | ERBB2 | |
| SCHEMBL9886530 | 0.77 | ERBB2 (0.34) | ERBB2 | |
| SCHEMBL11492401 | 0.74 | MAOA (0.41) | ACHEBACE1ERBB2MAOAMAOB | |
| SCHEMBL22980337 | 0.74 | ERBB2 (0.35) | ACHEBACE1ERBB2TDP1MEN1 | |
| SCHEMBL973343 | 0.73 | ACHE (0.57) | ACHEBACE1ERBB2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787122-B | Novel fold condensation of 2-methoxymethyl-p-phenylenediamine | 威娜德国有限责任公司 | 2025-03-21 | — | — | CN | claimed |
| EP-4013739-B1 | NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE | WELLA GERMANY GMBH (DE) | 2024-10-02 | — | — | EP | claimed |
| CN-114787122-A | Novel polycondensation synthesis of 2-methoxymethyl-p-phenylenediamine | 威娜德国有限责任公司 | 2022-07-22 | — | — | CN | claimed |
| EP-2646408-B1 | PROCESS FOR THE PREPARATION OF 2-METHOXYMETHYL-1,4-BENZENEDIAMINE, ITS DERIVATIVES THEREOF AND THE SALTS THEREOF | PROCTER & GAMBLE (US) | 2016-10-19 | — | — | EP | claimed |
| CN-103249711-B | Process for preparing 2-methoxymethyl-1, 4-benzenediamine, derivatives thereof and salts thereof | PROCTER & GAMBLE | 2015-01-28 | — | — | CN | claimed |
| US-8592631-B2 | Process for the preparation of 2-methoxymethy1-1,4-benzenediamine, its derivatives thereof and the salts thereof | THE PROCTER & GAMBLE COMPANY (US) | 2013-11-26 | — | — | US | claimed |
| EP-2646408-A1 | PROCESS FOR THE PREPARATION OF 2-METHOXYMETHYL-1,4-BENZENEDIAMINE, ITS DERIVATIVES THEREOF AND THE SALTS THEREOF | The Procter and Gamble Company (US) | 2013-10-09 | — | — | EP | claimed |
| CN-103249711-A | Process for preparing 2-methoxymethyl-1, 4-benzenediamine, derivatives thereof and salts thereof | PROCTER & GAMBLE | 2013-08-14 | — | — | CN | claimed |
| WO-2012074536-A1 | PROCESS FOR THE PREPARATION OF 2-METHOXYMETHYL-1,4-BENZENEDIAMINE, ITS DERIVATIVES THEREOF AND THE SALTS THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2012-06-07 | — | — | WO | claimed |
| US-20120142969-A1 | Process for the Preparation of 2-Methoxymethyl-1,4-Benzenediamine, Its Derivatives Thereof and the Salts Thereof | WELLA OPERATIONS US, LLC | 2012-06-07 | — | — | US | claimed |
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | claimed |
| CN-114787122-B | Novel fold condensation of 2-methoxymethyl-p-phenylenediamine | 威娜德国有限责任公司 | 2025-03-21 | — | — | CN | disclosed |
| US-12122734-B2 | Telescoping syntheses of 2-methoxymethyl-p-phenylenediamine | WELLA GERMANY GMBH (DE) | 2024-10-22 | — | — | US | disclosed |
| EP-4013739-B1 | NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE | WELLA GERMANY GMBH (DE) | 2024-10-02 | — | — | EP | disclosed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | disclosed |
| US-5053053-A | PROCESS FOR DYEING KERATINOUS FIBRES WITH A HYDROXYINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE; AND NOVEL 1,4-BENZOQUINONES | L'OREAL (FR) | 1991-10-01 | — | — | US | disclosed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12122734-B2 | Telescoping syntheses of 2-methoxymethyl-p-phenylenediamine | PNMT, TYR, DDT | ACHE 1837/4885BACE1 1325/4885ERBB2 588/4885 |
| US-20120142969-A1 | Process for the Preparation of 2-Methoxymethyl-1,4-Benzenediamine, Its Derivatives Thereof and the Salts Thereof | KRT18, VIM, KDM4B | ACHE 2390/4885BACE1 3719/4885ERBB2 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.