Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789498 | 0.94 | RAB9A (0.41) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL806791 | 0.87 | PI4KA (0.43) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL807161 | 0.86 | PIK3C3 (0.49) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL791568 | 0.85 | PI4KA (0.43) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL807111 | 0.85 | RAB9A (0.46) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL789808 | 0.85 | PIK3CG (0.44) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL790545 | 0.84 | PIK3C3 (0.44) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL807023 | 0.84 | PIK3CG (0.49) | RAB9API4KAPIK3CGPIK3C3 | |
| SCHEMBL12474809 | 0.84 | PI4KA (0.41) | ALDH1A1RAB9AKDM4EPOLBPI4KA | |
| SCHEMBL789741 | 0.84 | PI4KA (0.46) | ALDH1A1RAB9AKDM4EPOLBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |