Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672596 | 0.77 | SLC6A3 (0.81) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL987779 | 0.77 | MAOA (0.61) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL8352672 | 0.77 | MAOA (0.61) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL17402654 | 0.77 | MAOA (0.35) | MAOAMAOBTAAR1SLC6A3SLC6A4 | |
| SCHEMBL1672926 | 0.77 | SLC6A3 (0.81) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL14710296 | 0.77 | SLC6A4 (0.37) | MAOAMAOBTAAR1SLC6A3SLC6A4 | |
| SCHEMBL12928 | 0.77 | MAOA (0.61) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL1492704 | 0.76 | MAOB (1.00) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| Hydrochloric Acid SCHEMBL15757515 | 0.76 | SLC6A3 (0.78) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6813615 | 0.74 | MAOB (0.95) | MAOAMAOBTAAR1DPP4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100606-A1 | NOVEL PHENYL IMIDAZOLES AND PHENYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS | PFIZER INC. (US) | 2010-09-10 | — | — | WO | disclosed |