Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 7/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055234 | 0.79 | ESR2 (0.48) | SLC6A4SLC6A2MAOAMAOBTAAR1 | |
| SCHEMBL3615305 | 0.77 | SLC6A4 (0.52) | SLC6A4SLC6A2MAOAMAOBPRKAB2 | |
| SCHEMBL8353941 | 0.77 | L3MBTL1 (0.41) | SLC6A4SLC6A2MAOAMAOBTAAR1 | |
| SCHEMBL4275 | 0.77 | ALDH1A1 (0.38) | SLC6A4SLC6A2MAOAMAOBTAAR1 | |
| SCHEMBL7704791 | 0.77 | SLC6A3 (0.52) | SLC6A4SLC6A2MAOAMAOBPRKAB2 | |
| SCHEMBL5645623 | 0.77 | SLC6A2 (0.37) | SLC6A4SLC6A2MAOAMAOBTAAR1 | |
| SCHEMBL7898281 | 0.77 | MAOA (0.61) | SLC6A4SLC6A2MAOAMAOBTAAR1 | |
| SCHEMBL17402654 | 0.77 | MAOA (0.35) | SLC6A4SLC6A2MAOAMAOBTAAR1 | |
| SCHEMBL1371770 | 0.76 | MAOA (0.60) | SLC6A4SLC6A2MAOAMAOBTAAR1 | |
| SCHEMBL2317613 | 0.74 | ENPP2 (0.39) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |