Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511166 | 0.85 | NCEH1 (0.39) | MTNR1ATDP1KDM4ECYP1A2TP53 | |
| SCHEMBL9511619 | 0.76 | CA12 (0.51) | TDP1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL27776801 | 0.76 | NPC1 (0.47) | TDP1TP53MEN1KMT2A | |
| SCHEMBL8751582 | 0.74 | HCRTR1 (0.54) | MTNR1ATDP1MCL1KDM4ECYP1A2 | |
| SCHEMBL961507 | 0.73 | MTNR1A (0.63) | MTNR1ATDP1COPS5KDM4ECYP1A2 | |
| Urea SCHEMBL15059663 | 0.73 | MTNR1A (0.63) | MTNR1ATDP1MCL1COPS5CYP1A2 | |
| SCHEMBL1990599 | 0.72 | ADRA2C (0.50) | TP53MEN1KMT2A | |
| SCHEMBL5742511 | 0.72 | ADRA2C (0.54) | TP53MEN1KMT2A | |
| SCHEMBL18929757 | 0.71 | CYP1A2 (0.53) | MTNR1ATDP1KDM4ECYP1A2CDYL | |
| SCHEMBL1284856 | 0.71 | MTNR1A (0.62) | MTNR1ATDP1MCL1COPS5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | disclosed |