Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562866 | 0.99 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL6562939 | 0.94 | ALDH1A1 (0.54) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL8581694 | 0.94 | ALDH1A1 (0.54) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL9829273 | 0.94 | ALDH1A1 (0.54) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL7896986 | 0.94 | ALDH1A1 (0.54) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL6561332 | 0.92 | TSHR (0.53) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL9832137 | 0.92 | ALDH1A1 (0.56) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL7897832 | 0.92 | ALDH1A1 (0.56) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| Benzene SCHEMBL28226142 | 0.91 | PSMB5 (0.55) | SMN1; SMN2GAAALOX15PSMB5MAPK1 | |
| SCHEMBL25045739 | 0.89 | KMT2A (0.56) | SMN1; SMN2GAAALOX15PSMB5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180140-B1 | SUITABLE FOR ORAL ADMINISTRATION OF BIOLOGICALLY ACTIVE AGENTS TO ANIMALS | EMISPHERE TECHNOLOGIES, INC. | 2001-01-30 | — | — | US | disclosed |
| US-5935601-A | Modified amino acids for drug delivery | EMISPHERE TECHNOLOGIES, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0812212-A4 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | EMISPHERE TECH INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0758843-A4 | MODIFIED AMINO ACIDS FOR DRUG DELIVERY | EMISPHERE TECH INC (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5709861-A | PEPTIDES WITH ANTIGENS AND PROCESS FOR MIXING | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0812212-A1 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | Emisphere Technologies, Inc. (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5629020-A | Modified amino acids for drug delivery | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0758843-A1 | MODIFIED AMINO ACIDS FOR DRUG DELIVERY | Emisphere Technologies, Inc. (US) | 1997-02-26 | — | — | EP | disclosed |
| WO-1996021464-A9 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | — | 1996-11-14 | — | — | WO | disclosed |
| WO-1996021464-A1 | COMPOSITIONS FOR THE DELIVERY OF ANTIGENS | EMISPHERE TECHNOLOGIES, INC. (US) | 1996-07-18 | — | — | WO | disclosed |
| WO-1995028838-A1 | MODIFIED AMINO ACIDS FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1995-11-02 | — | — | WO | disclosed |