Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 10/20 | 0.81 |
| ▸ | TRPC6 | Q9Y210 | 10/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788828 | 0.87 | TRPC3 (0.78) | TRPC3TRPC6TSHRMEN1KMT2A | |
| SCHEMBL789564 | 0.87 | TRPC3 (1.00) | TRPC3TRPC6TSHRTRPA1CACNA1C | |
| SCHEMBL10087858 | 0.83 | TRPC3 (0.58) | TRPC3TRPC6TSHRTRPA1CACNA1C | |
| SCHEMBL789503 | 0.78 | TRPC3 (1.00) | TRPC3TRPC6TSHRTRPA1CACNA1C | |
| SCHEMBL5200233 | 0.78 | MAPT (0.68) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL3540590 | 0.78 | ALDH1A1 (0.61) | TRPC3TRPC6TSHRMEN1KMT2A | |
| SCHEMBL789085 | 0.76 | NPC1 (0.98) | TRPC3TRPC6TSHRMEN1KMT2A | |
| SCHEMBL29944255 | 0.75 | NPC1 (0.57) | TRPC3TRPC6TSHRMEN1KMT2A | |
| SCHEMBL20600073 | 0.73 | TRPC3 (0.58) | TRPC3TRPC6TSHRTRPA1CACNA1C | |
| SCHEMBL21708021 | 0.73 | MAPT (0.68) | MEN1KMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | claimed |
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |