SCHEMBL7898730

SCHEMBL7898730

Cc1ccc(I)c(-c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC7 Q8WUI4 1/20 0.49
PSMB5 P28074 1/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.46
ELANE P08246 1/20 0.43
MAOB P27338 2/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
BACE1 P56817 1/20 0.41
ESR2 Q92731 1/20 0.41
METAP2 P50579 1/20 0.41
HPRT1 P00492 1/20 0.41
C1R P00736 1/20 0.41
CYP2A6 P11509 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28492839 0.94 HDAC7 (0.49) HDAC7PSMB5PTGDR2ELANEMAOB
SCHEMBL28807429 0.86 MAOB (0.40) HDAC7ELANEMAOBKDM4EALDH1A1
SCHEMBL24656816 0.85 HPRT1 (0.53) PSMB5MAOBKDM4EALDH1A1L3MBTL1
SCHEMBL15000652 0.84 PSMB5 (0.46) HDAC7PSMB5PTGDR2ELANEMAOB
SCHEMBL19975717 0.84 ACHE (0.46) MAOBALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL3005820 0.81 ELANE (0.52) HDAC7PSMB5PTGDR2ELANEMAOB
SCHEMBL24656817 0.79 HDAC7 (0.44) HDAC7PSMB5PTGDR2ELANEMAOB
SCHEMBL24346062 0.79 ACHE (0.38) ELANEMAOBALDH1A1C1RCYP2A6
SCHEMBL21333851 0.79 METAP2 (0.50) HDAC7PSMB5PTGDR2MAOBALDH1A1
SCHEMBL8056200 0.79 ELANE (0.50) HDAC7PSMB5PTGDR2ELANEMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112135598-B Macromer-based photocurable dental impression material 登士柏希罗纳有限公司 2023-12-22 CN disclosed
CN-113692269-B Dental composition 登士柏希罗纳有限公司 2023-10-27 CN disclosed
US-10032985-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-07-24 US disclosed
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10032985-B2 Condensed cyclic compound and organic light-emitting device including the same CCNT1, CCNA1, CRY1 HDAC7 4652/4885PSMB5 2905/4885PTGDR2 706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.