Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713264 | 0.83 | GABRA1 (0.37) | FSCN1GABRA1GABRA5GRIN1GRIN2B | |
| SCHEMBL615854 | 0.82 | L3MBTL1 (0.36) | FSCN1OPRM1METGABRA1GABRA5 | |
| SCHEMBL7913305 | 0.76 | GABRA1 (0.41) | FSCN1GABRA1GABRA5 | |
| SCHEMBL615038 | 0.73 | FGFR1 (0.38) | FSCN1MET | |
| SCHEMBL14875518 | 0.69 | GRM2 (0.39) | FSCN1 | |
| SCHEMBL7900281 | 0.68 | FSCN1 (0.34) | FSCN1 | |
| SCHEMBL3708584 | 0.68 | F2RL3 (0.41) | FSCN1GABRA1GABRA5PTGS2 | |
| SCHEMBL617119 | 0.68 | FSCN1 (0.41) | FSCN1 | |
| SCHEMBL7906411 | 0.66 | FGFR1 (0.47) | MET | |
| SCHEMBL7901453 | 0.62 | CHRM1 (0.42) | FSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096338-A1 | PYRAZOLO [4,3-c] CINNOLIN-3-ONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2010-08-26 | — | — | WO | disclosed |