Known targets — ChEMBL curated mechanism
DHFRGARTPTGFRPTGIRPTGS1PTGS2TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8envmurAthyA
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | EYA2 | O00167 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL49456 | 0.94 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1668331 | 0.88 | TDP1 (0.56) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL5470836 | 0.88 | TDP1 (0.56) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9048495 | 0.88 | TDP1 (0.56) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9225789 | 0.86 | TDP1 (0.54) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9176717 | 0.85 | TDP1 (0.52) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL11797803 | 0.83 | TDP1 (0.50) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL7899139 | 0.83 | TDP1 (0.45) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL247531 | 0.82 | TDP1 (0.82) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL30569658 | 0.82 | TDP1 (0.82) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3777 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630872-B1 | Method for detecting a targeted nucleic acid from a deoxyribonucleic acid (DNA) sample extracted using a DNA extraction kit through DNA amplification testing | Biosci RD Corporation (US) | 2026-05-19 | — | — | US | claimed |
| CN-122031708-A | Cascade double-and logic DNA nano circuit and preparation method and application thereof | 南方医科大学珠江医院 | 2026-05-15 | — | — | CN | claimed |
| CN-122012611-A | DNA nanostructure carrier, DNA nano medicine and application thereof | 北京君全智药生物科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-121575133-A | Salmonella live bacteria detection system based on deoxyribozyme activation and method thereof | 湖南工程学院 | 2026-02-27 | — | — | CN | claimed |
| US-20260002904-A1 | MICROFLUIDIC ELECTROPHORESIS-MEDIATED CHARACTERIZATION OF PLASMID DNA ISOFORMS | REVVITY HEALTH SCIENCES INC (US) | 2026-01-01 | — | — | US | claimed |
| US-20250345797-A1 | MICROFLUIDIC DEVICES AND METHODS FOR SORTING PARTICLES SUCH AS EXTRACELLULAR VESICLES IN A SAMPLE | UNIV HONG KONG SCIENCE & TECH (CN) | 2025-11-13 | — | — | US | claimed |
| WO-2025222268-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING ATROPHIC VAGINITIS | JASTLABS CORPORATION (CA) | 2025-10-30 | — | — | WO | claimed |
| EP-4605562-A1 | A METHOD FOR DETECTING THE PRESENCE OF A DENGUE VIRUS SEROTYPE IN A SAMPLE CONTAINING AT LEAST ONE DENGUE VIRUS SEROTYPE | Takeda Vaccines, Inc. (US) | 2025-08-27 | — | — | EP | claimed |
| CN-120142640-A | Double-effect hydrogel fluorescence sensing method for detecting tetracycline and application thereof | 太原理工大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120081915-A | Construction method and application of Crimedes-Congo hemorrhagic fever virus (CCHFV) virus-like particle (VLP) | 湖北江夏实验室 | 2025-06-03 | — | — | CN | claimed |
| CN-114487441-A | Method for evaluating kidney aging | 暨赛国际再生医学科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114480580-A | Method for evaluating liver aging | 暨赛国际再生医学科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| WO-2022081741-A1 | ELECTROPHORETIC DEVICES AND METHODS FOR NEXT-GENERATION SEQUENCING LIBRARY PREPARATION | Roche Sequencing Solutions, Inc. (US) | 2022-04-21 | — | — | WO | claimed |
| US-20220111386-A1 | CONCENTRATION ENRICHMENT, SEPARATION AND CATION EXCHANGE IN WATER-IN-OIL DROPLETS | NATIONAL SCIENCE FOUNDATION | 2022-04-14 | — | — | US | claimed |
| CN-114292842-A | Amplification primer and detection method for realizing specific qualitative PCR detection of transgenic corn 2A-7 transformation event | 四川省农业科学院农业质量标准与检测技术研究所 | 2022-04-08 | — | — | CN | claimed |
| CN-113417009-B | Method for guiding nano particle superlattice by using DNA origami and DNA tiles | 南京大学 | 2022-04-05 | — | — | CN | claimed |
| CN-109694922-B | Characteristic sequence, labeled primer and identification method of pecan variety dependendable | 浙江省林业科学研究院 | 2022-03-29 | — | — | CN | claimed |
| US-20220090063-A1 | CRISPR/CAS9 IN VITRO KIT | WISYS TECH FOUNDATION INC (US) | 2022-03-24 | — | — | US | claimed |
| CN-109694923-B | Characteristic sequence, marker primer and identification method of apocarya variety Jingzhou No. 1 | 浙江省林业科学研究院 | 2022-03-22 | — | — | CN | claimed |
| CN-111549173-B | Indel labeled primer pair and method for identifying purity of cucumber Lumei No.1 hybrid seeds | 江苏绿港现代农业发展股份有限公司 | 2022-03-15 | — | — | CN | claimed |