Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878683 | 0.81 | USP2 (0.39) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL16583210 | 0.78 | USP2 (0.39) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL31555840 | 0.78 | ESR2 (0.39) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL975177 | 0.78 | HPGD (0.37) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL4762097 | 0.75 | USP2 (0.41) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL25047980 | 0.74 | CTSK (0.39) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL31555855 | 0.74 | BTK (0.47) | MEN1KMT2AESR2BTKGPR119 | |
| SCHEMBL2980997 | 0.74 | ESR2 (0.43) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL17481737 | 0.74 | USP2 (0.41) | USP2SMN1; SMN2MEN1KMT2AESR2 | |
| SCHEMBL7863282 | 0.73 | GLA (0.46) | SMN1; SMN2MEN1KMT2ACTSKGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |