SCHEMBL7863282

SCHEMBL7863282

CCOC(=O)C1=CN(C(=O)OC(C)(C)C)CCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.46
ADORA1 P30542 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GPR119 Q8TDV5 2/20 0.37
GAA P10253 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ATM Q13315 1/20 0.36
MAPK1 P28482 2/20 0.36
CTSK P43235 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31195159 0.81 ADORA1 (0.48) GLAADORA1MEN1KMT2AGPR119
SCHEMBL28213798 0.78 TSHR (0.40) GLAALDH1A1LMNASMN1; SMN2MAPK1
SCHEMBL17942008 0.78 L3MBTL1 (0.38) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL14878683 0.77 USP2 (0.39) MEN1KMT2AGPR119SMN1; SMN2CTSK
SCHEMBL12931062 0.75 ADORA1 (0.53) GLAADORA1MEN1KMT2AGPR119
SCHEMBL630338 0.74 ADORA1 (0.49) GLAADORA1MEN1KMT2AGPR119
SCHEMBL7899134 0.73 USP2 (0.38) MEN1KMT2AGPR119ALDH1A1LMNA
SCHEMBL20670426 0.73 GLA (0.42) GLAADORA1MEN1KMT2AGPR119
SCHEMBL29099338 0.72 GLA (0.43) GLAADORA1MEN1KMT2AGPR119
SCHEMBL6541860 0.72 ADORA1 (0.47) GLAADORA1MEN1KMT2AGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010041720-A1 Compound with growth hormone releasing properties NOVO NORDISK A/S (DK) 2001-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010041720-A1 Compound with growth hormone releasing properties GHRHR, GHSR, PRLHR GLA 1079/4885ADORA1 544/4885MEN1 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.