Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.76 |
| ▸ | MMP1 | P03956 | 8/20 | 0.76 |
| ▸ | MMP13 | P45452 | 8/20 | 0.76 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.58 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931438 | 0.90 | MMP9 (0.75) | MMP9MMP1MMP13ADAM17NAMPT | |
| Hydroxyamine SCHEMBL7555703 | 0.89 | MMP9 (0.78) | MMP9MMP1MMP13ADAM17NAMPT | |
| SCHEMBL6932299 | 0.89 | MMP9 (0.80) | MMP9MMP1MMP13ADAM17NAMPT | |
| SCHEMBL6932325 | 0.86 | MMP9 (1.00) | MMP9MMP1MMP13ADAM17NAMPT | |
| SCHEMBL7702807 | 0.85 | MMP9 (0.61) | MMP9MMP1MMP13ADAM17NAMPT | |
| SCHEMBL7557253 | 0.85 | MMP13 (0.76) | MMP9MMP1MMP13ADAM17NAMPT | |
| SCHEMBL7658073 | 0.83 | MMP9 (0.77) | MMP9MMP1MMP13ADAM17NAMPT | |
| SCHEMBL7701550 | 0.82 | MMP9 (0.69) | MMP9MMP1MMP13ADAM17NAMPT | |
| SCHEMBL6935134 | 0.76 | MMP9 (0.80) | MMP9MMP1MMP13ADAM17NAMPT | |
| Hydroxyamine SCHEMBL7557247 | 0.76 | MMP13 (0.78) | MMP9MMP1MMP13ADAM17NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197791-B1 | ANTIARTHRITIC AGENTS; WOUND HEALING AGENTS; ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY | 2001-03-06 | — | — | US | disclosed |