Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 10/20 | 0.61 |
| ▸ | MMP13 | P45452 | 9/20 | 0.61 |
| ▸ | MMP1 | P03956 | 8/20 | 0.61 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.61 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934187 | 0.91 | MMP9 (0.61) | MMP9MMP13MMP1ADAM17NAMPT | |
| Hydroxyamine SCHEMBL7702805 | 0.91 | MMP9 (0.62) | MMP9MMP13MMP1ADAM17NAMPT | |
| SCHEMBL6930534 | 0.91 | MMP9 (0.64) | MMP9MMP13MMP1ADAM17NAMPT | |
| SCHEMBL6930135 | 0.88 | MMP9 (0.77) | MMP9MMP13MMP1ADAM17NAMPT | |
| SCHEMBL7658073 | 0.87 | MMP9 (0.77) | MMP9MMP13MMP1ADAM17NAMPT | |
| SCHEMBL7557253 | 0.87 | MMP13 (0.76) | MMP9MMP13MMP1ADAM17NAMPT | |
| SCHEMBL7899148 | 0.85 | MMP9 (0.76) | MMP9MMP13MMP1ADAM17NAMPT | |
| SCHEMBL6932872 | 0.81 | MMP1 (0.49) | MMP9MMP13MMP1ADAM17NAMPT | |
| Hydroxyamine SCHEMBL7551667 | 0.80 | MMP1 (0.49) | MMP9MMP13MMP1ADAM17NAMPT | |
| SCHEMBL6929990 | 0.80 | MMP1 (0.50) | MMP9MMP13MMP1ADAM17NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342508-B1 | ENZYME INHIBITORS FOR PROTECTION OF CONNECTIVE TISSUES | AMERICAN CYANAMID COMPANY | 2002-01-29 | — | — | US | disclosed |