Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614498 | 0.91 | LIMK1 (0.67) | LIMK1LIMK2GABRA1GABRG2GABRB3 | |
| SCHEMBL615545 | 0.80 | MAOA (0.53) | LIMK1LIMK2GABRA1GABRG2GABRB3 | |
| SCHEMBL5879186 | 0.74 | MAOA (0.58) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL613137 | 0.73 | LIMK1 (0.68) | LIMK1LIMK2ALDH1A1MAPTHPGD | |
| SCHEMBL612219 | 0.72 | LIMK1 (1.00) | LIMK1LIMK2CHEK1ALDH1A1MAPT | |
| SCHEMBL5879315 | 0.70 | MAOB (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18796679 | 0.70 | MAOA (0.62) | MAOAMAOBTRPM8CTSVCTSL | |
| SCHEMBL10022322 | 0.70 | CHEK1 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL25904061 | 0.69 | MAOA (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11160990 | 0.69 | KIT (0.69) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010095042-A2 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-08-26 | — | — | WO | disclosed |