Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | CTSV | O60911 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614498 | 0.84 | LIMK1 (0.67) | MAOAMAOBCTSVCTSLIP6K1 | |
| SCHEMBL11077910 | 0.82 | STING1 (0.54) | LIMK1LIMK2KDM4EMAPTLMNA | |
| SCHEMBL7899171 | 0.80 | LIMK1 (0.56) | MAOAMAOBCTSVCTSLLIMK1 | |
| SCHEMBL614042 | 0.79 | MAOA (0.55) | MAOAMAOBCTSVCTSLTRPM8 | |
| SCHEMBL613815 | 0.78 | MAOA (0.54) | MAOAMAOBTRPM8KDM4EMAPT | |
| SCHEMBL11081378 | 0.78 | NQO2 (0.51) | LIMK1LIMK2KDM4EMAPTLMNA | |
| SCHEMBL10022323 | 0.73 | MAOA (0.47) | MAOAMAOBCTSVCTSLTRPM8 | |
| SCHEMBL5504619 | 0.73 | KDM4E (0.69) | MAOAMAOBCTSVCTSLTRPM8 | |
| SCHEMBL18796679 | 0.73 | MAOA (0.62) | MAOAMAOBCTSVCTSLTRPM8 | |
| SCHEMBL5879186 | 0.72 | MAOA (0.58) | MAOAMAOBCTSVCTSLIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604048-B2 | Pyridocarbazole type compounds and applications thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-10 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| WO-2010095042-A2 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | NLN, OPA1, PYCR1 | MAOA 331/4885MAOB 248/4885CTSV 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.