Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.81 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985362 | 0.93 | OPRD1 (0.71) | OPRD1MAPK14KDM4EGLASMN1; SMN2 | |
| SCHEMBL8985273 | 0.91 | OPRD1 (0.67) | OPRD1MAPK14KDM4EGLASMN1; SMN2 | |
| SCHEMBL1847221 | 0.84 | OPRD1 (0.59) | OPRD1MAPK14KDM4EGLASMN1; SMN2 | |
| SCHEMBL2159048 | 0.84 | OPRD1 (0.59) | OPRD1MAPK14KDM4EGLASMN1; SMN2 | |
| SCHEMBL8985468 | 0.84 | OPRD1 (0.70) | OPRD1MAPK14KDM4ESMN1; SMN2EP300 | |
| SCHEMBL8985511 | 0.84 | OPRD1 (0.74) | OPRD1KDM4EGLASMN1; SMN2EP300 | |
| SCHEMBL1851230 | 0.83 | OPRD1 (0.57) | OPRD1MAPK14KDM4EGLASMN1; SMN2 | |
| SCHEMBL6251131 | 0.82 | MAPK14 (0.60) | OPRD1MAPK14KDM4EPTGS1PTGS2 | |
| SCHEMBL3604294 | 0.82 | OPRD1 (0.56) | OPRD1MAPK14KDM4EGLASMN1; SMN2 | |
| SCHEMBL8985383 | 0.81 | MAPK14 (0.70) | OPRD1MAPK14KDM4ESMN1; SMN2EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37078-E1 | Thiophene compounds | ADIR ET COMPAGNIE (FR) | 2001-02-27 | — | — | US | disclosed |
| US-5705525-A | ANTIINFLAMMATORY AGENTS AND TREATMENT OF RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1998-01-06 | — | — | US | disclosed |