Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899259 | 0.93 | OPRD1 (0.81) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985383 | 0.89 | MAPK14 (0.70) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985342 | 0.89 | MAPK14 (0.83) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985276 | 0.86 | OPRD1 (0.66) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985484 | 0.86 | OPRD1 (0.62) | OPRD1MAPK14PTGS1PTGS2EP300 | |
| SCHEMBL1848218 | 0.85 | OPRD1 (0.55) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985273 | 0.84 | OPRD1 (0.67) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985409 | 0.84 | MAPK14 (0.75) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985288 | 0.81 | MAPK14 (0.67) | OPRD1MAPK14PTGS1PTGS2KDM4E | |
| SCHEMBL8985510 | 0.81 | MAPK14 (0.67) | OPRD1MAPK14PTGS1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |