Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985516 | 0.90 | MAPK14 (0.83) | MAPK14OPRD1PTGS2PTGS1KDM4E | |
| SCHEMBL8985362 | 0.89 | OPRD1 (0.71) | MAPK14OPRD1PTGS2PTGS1EP300 | |
| SCHEMBL8985484 | 0.86 | OPRD1 (0.62) | MAPK14OPRD1PTGS2PTGS1EP300 | |
| SCHEMBL8985276 | 0.86 | OPRD1 (0.66) | MAPK14OPRD1PTGS2PTGS1EP300 | |
| SCHEMBL8985533 | 0.84 | OPRD1 (0.64) | MAPK14OPRD1PTGS2PTGS1EP300 | |
| SCHEMBL8985409 | 0.84 | MAPK14 (0.75) | MAPK14OPRD1PTGS2PTGS1EP300 | |
| SCHEMBL8985250 | 0.83 | MAPK14 (0.73) | MAPK14OPRD1PTGS2PTGS1KDM4E | |
| SCHEMBL8985453 | 0.83 | OPRD1 (0.62) | MAPK14OPRD1PTGS2PTGS1EP300 | |
| SCHEMBL17542551 | 0.82 | MAPK14 (1.00) | MAPK14PTGS2PTGS1 | |
| SCHEMBL8985373 | 0.82 | OPRD1 (0.61) | MAPK14OPRD1PTGS2PTGS1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |