Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.89 |
| ▸ | BLM | P54132 | 1/20 | 0.89 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | THPO | P40225 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789557 | 0.98 | DRD3 (0.86) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL4709602 | 0.94 | BLM (1.00) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL18464 | 0.94 | BLM (1.00) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL4383022 | 0.92 | BLM (0.96) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL5309668 | 0.92 | BLM (0.96) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL4562808 | 0.92 | BLM (0.96) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL317195 | 0.92 | BLM (0.96) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL1231172 | 0.92 | BLM (0.96) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL4732534 | 0.92 | BLM (0.96) | DRD3BLMCA12F13A1CA2 | |
| Amifostine SCHEMBL20213780 | 0.91 | BLM (0.93) | DRD3BLMCA12F13A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632419-B1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | UNIV CHICAGO (US) | 2022-12-28 | — | — | EP | claimed |
| EP-1437139-B1 | Method for protection against genotoxic mutagenesis | ARCH DEV CORP (US) | 2008-07-16 | — | — | EP | claimed |
| EP-1437139-A2 | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 2004-07-14 | — | — | EP | claimed |
| US-5869338-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1999-02-09 | — | — | US | claimed |
| EP-0764027-A4 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEV CORP (US) | 1998-04-22 | — | — | EP | claimed |
| EP-0764027-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1997-03-26 | — | — | EP | claimed |
| US-5567686-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1996-10-22 | — | — | US | claimed |
| US-5488042-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1996-01-30 | — | — | US | claimed |
| WO-1995007700-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1995-03-23 | — | — | WO | claimed |
| WO-1993017689-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1993-09-16 | — | — | WO | claimed |
| EP-3632419-B1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | UNIV CHICAGO (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20210244751-A1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | THE UNIVERSITY OF CHICAGO (US) | 2021-08-12 | — | — | US | disclosed |
| US-10987366-B2 | Methods and compositions for protection of cells and tissues from computed tomography radiation | THE UNIVERSITY OF CHICAGO (US) | 2021-04-27 | — | — | US | disclosed |
| EP-3632419-A1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | The University of Chicago (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-2663297-B1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | UNIV CHICAGO (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-0764027-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5567686-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| US-5488042-A | Method for protection against genotoxic mutagenesis | ARCH DEVELOPMENT CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1995007700-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1995-03-23 | — | — | WO | disclosed |
| WO-1993017689-A1 | METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS | ARCH DEVELOPMENT CORPORATION (US) | 1993-09-16 | — | — | WO | disclosed |