SCHEMBL789557

SCHEMBL789557

NCCCCCNCCSP(=O)(O)O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.86
BLM P54132 1/20 0.86
CA12 O43570 2/20 0.46
F13A1 P00488 2/20 0.46
CA2 P00918 2/20 0.46
CYP1A2 P05177 2/20 0.46
ALOX15 P16050 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
THPO P40225 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
CA1 P00915 1/20 0.46
CA3 P07451 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL789954 0.98 DRD3 (0.89) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL18464 0.92 BLM (1.00) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL4709602 0.92 BLM (1.00) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL4383022 0.91 BLM (0.96) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL4732534 0.91 BLM (0.96) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL1231172 0.91 BLM (0.96) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL5309668 0.91 BLM (0.96) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL317195 0.91 BLM (0.96) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL4562808 0.91 BLM (0.96) DRD3BLMCA12F13A1CA2
Amifostine SCHEMBL20213780 0.89 BLM (0.93) DRD3BLMCA12F13A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3632419-B1 METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION UNIV CHICAGO (US) 2022-12-28 EP claimed
EP-1437139-B1 Method for protection against genotoxic mutagenesis ARCH DEV CORP (US) 2008-07-16 EP claimed
EP-1437139-A2 Method for protection against genotoxic mutagenesis ARCH DEVELOPMENT CORPORATION (US) 2004-07-14 EP claimed
US-5891856-A Method for protection against genotoxic mutagenesis ARCH DEVELOPMENT CORPORATION (US) 1999-04-06 US claimed
US-5869338-A Method for protection against genotoxic mutagenesis ARCH DEVELOPMENT CORPORATION (US) 1999-02-09 US claimed
EP-0764027-A4 METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS ARCH DEV CORP (US) 1998-04-22 EP claimed
EP-0764027-A1 METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS ARCH DEVELOPMENT CORPORATION (US) 1997-03-26 EP claimed
US-5567686-A Method for protection against genotoxic mutagenesis ARCH DEVELOPMENT CORPORATION (US) 1996-10-22 US claimed
US-5488042-A Method for protection against genotoxic mutagenesis ARCH DEVELOPMENT CORPORATION (US) 1996-01-30 US claimed
WO-1995007700-A1 METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS ARCH DEVELOPMENT CORPORATION (US) 1995-03-23 WO claimed
WO-1993017689-A1 METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS ARCH DEVELOPMENT CORPORATION (US) 1993-09-16 WO claimed
CN-110964796-B Large-scale parallel single cell analysis 贝克顿迪金森公司 2024-04-05 CN disclosed
CN-116529254-A Phosphonate products and methods 伊利诺伊大学董事会 2023-08-01 CN disclosed
EP-3632419-B1 METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION UNIV CHICAGO (US) 2022-12-28 EP disclosed
US-11484857-B2 Environmentally biodegradable microcapsules TRUCAPSOL LLC (US) 2022-11-01 US disclosed
EP-0764027-A1 METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS ARCH DEVELOPMENT CORPORATION (US) 1997-03-26 EP disclosed
US-5567686-A Method for protection against genotoxic mutagenesis ARCH DEVELOPMENT CORPORATION (US) 1996-10-22 US disclosed
US-5488042-A Method for protection against genotoxic mutagenesis ARCH DEVELOPMENT CORPORATION (US) 1996-01-30 US disclosed
WO-1995007700-A1 METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS ARCH DEVELOPMENT CORPORATION (US) 1995-03-23 WO disclosed
WO-1993017689-A1 METHOD FOR PROTECTION AGAINST GENOTOXIC MUTAGENESIS ARCH DEVELOPMENT CORPORATION (US) 1993-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11484857-B2 Environmentally biodegradable microcapsules MCM3, MAST3, EPM2A DRD3 3946/4885BLM 2516/4885CA12 3196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.