SCHEMBL7899541

SCHEMBL7899541

O=C(O)c1cccc(S(=O)(=O)Cl)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
TSHR P16473 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 2/20 0.43
F2 P00734 2/20 0.42
PRSS1 P07477 2/20 0.42
PRSS2 P07478 2/20 0.42
PRSS3 P35030 2/20 0.42
CA12 O43570 3/20 0.40
CA9 Q16790 3/20 0.40
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29443910 1.00 ALOX15 (0.46) ALOX15CA1CA2MMP1MMP2
Hydrochloric Acid SCHEMBL628150 0.98 ALOX15 (0.44) ALOX15CA1CA2MMP1MMP2
Hydrochloric Acid SCHEMBL3268906 0.98 ALOX15 (0.44) ALOX15CA1CA2MMP1MMP2
SCHEMBL347237 0.84 ALOX15 (0.48) ALOX15CA1CA2MMP1MMP2
SCHEMBL29435078 0.84 ALOX15 (0.48) ALOX15CA1CA2MMP1MMP2
SCHEMBL30842657 0.82 ALOX15 (0.47) ALOX15CA1CA2MMP1MMP2
SCHEMBL60211 0.82 ALOX15 (0.47) ALOX15CA1CA2MMP1MMP2
SCHEMBL135801 0.82 CA1 (0.60) ALOX15CA1CA2MMP1MMP2
SCHEMBL6153587 0.81 TSHR (0.57) ALOX15CA1CA2MMP1MMP2
SCHEMBL28205155 0.81 ALDH1A1 (0.50) ALOX15CA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110499091-A A kind of chitin modified polyphenyl sulfonamide antimicrobial coating of nano silver-and its preparation method WANG HUAN 2019-11-26 CN claimed
WO-2023176048-A1 COMPOSITE REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR 日東電工株式会社 2023-09-21 WO disclosed
WO-2023176049-A1 COMPOSITE REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR 日東電工株式会社 2023-09-21 WO disclosed
CN-110499091-A A kind of chitin modified polyphenyl sulfonamide antimicrobial coating of nano silver-and its preparation method WANG HUAN 2019-11-26 CN disclosed
CN-110499091-A A kind of chitin modified polyphenyl sulfonamide antimicrobial coating of nano silver-and its preparation method WANG HUAN 2019-11-26 CN disclosed
EP-3199225-A1 SPIRAL MEMBRANE ELEMENT Nitto Denko Corporation (JP) 2017-08-02 EP disclosed
US-6183498-B1 Methods and products for sealing a fluid leak in a tissue DEVORE DALE P (US) 2001-02-06 US disclosed
EP-0901383-A1 METHODS AND PRODUCTS FOR SEALING A FLUID LEAK IN A TISSUE C.R. BARD, INC. (US) 1999-03-17 EP disclosed
WO-1997042986-A1 METHODS AND PRODUCTS FOR SEALING A FLUID LEAK IN A TISSUE C. R. BARD, INC. (US) 1997-11-20 WO disclosed
US-4101551-A WATER INSOLUBILITY, AFFINITY FOR POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-4060549-A Process for preparing sulfonic acid fluorides BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed