Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.44 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 known ✓ | P45452 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3268906 | 1.00 | ALOX15 (0.44) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL29443910 | 0.98 | ALOX15 (0.46) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL7899541 | 0.98 | ALOX15 (0.46) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL347237 | 0.82 | ALOX15 (0.48) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL29435078 | 0.82 | ALOX15 (0.48) | ALOX15CA1CA2MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL3893485 | 0.82 | CA1 (0.58) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL60211 | 0.81 | ALOX15 (0.47) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL30842657 | 0.81 | ALOX15 (0.47) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL135801 | 0.80 | CA1 (0.60) | ALOX15CA1CA2MMP1MMP2 | |
| SCHEMBL3183954 | 0.79 | ALOX15 (0.46) | ALOX15CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115845615-A | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115228290-A | Preparation method of cleaning-resistant reverse osmosis membrane | 万华化学集团股份有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-114146566-A | Preparation method of high-performance polyolefin substrate reverse osmosis membrane, reverse osmosis membrane and application | 万华化学集团股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-114146567-A | Preparation process of epoxy modified reverse osmosis membrane, reverse osmosis membrane and application of reverse osmosis membrane | 万华化学集团股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-110354682-B | Reverse osmosis membrane resisting biological pollution and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-112827368-A | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-05-25 | — | — | CN | claimed |
| EP-4176962-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE, SPIRAL MEMBRANE ELEMENT, WATER TREATMENT SYSTEM, AND WATER TREATMENT METHOD | NITTO DENKO CORP (JP) | 2026-01-28 | — | — | EP | disclosed |
| EP-3682964-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR MANUFACTURING SAME | NITTO DENKO CORP (JP) | 2025-06-18 | — | — | EP | disclosed |
| US-12239942-B2 | Separation membrane | NITTO DENKO CORPORATION (JP) | 2025-03-04 | — | — | US | disclosed |
| WO-2024122107-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL-TYPE MEMBRANE ELEMENT | 日東電工株式会社 | 2024-06-13 | — | — | WO | disclosed |
| CN-113600040-B | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-20230144222-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, SPIRAL MEMBRANE ELEMENT, WATER TREATMENT SYSTEM, AND WATER TREATMENT METHOD | NITTO DENKO CORPORATION (JP) | 2023-05-11 | — | — | US | disclosed |
| EP-4176962-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, SPIRAL MEMBRANE ELEMENT, WATER TREATMENT SYSTEM, AND WATER TREATMENT METHOD | NITTO DENKO CORPORATION (JP) | 2023-05-10 | — | — | EP | disclosed |
| US-20080053893-A1 | Semipermeable Composite Membrane and Process for Producing the Same | NITTO DENKO CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| EP-1825905-A1 | SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Nitto Denko Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| CN-101027116-A | Semipermeable composite membrane and process for producing the same | NITTO DENKO CORP (JP) | 2007-08-29 | — | — | CN | disclosed |
| CN-101027117-A | Semipermeable composite membrane and process for producing the same | NITTO DENKO CORP (JP) | 2007-08-29 | — | — | CN | disclosed |
| EP-1820566-A1 | SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Nitto Denko Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1808220-A1 | PROCESS FOR PRODUCING COMPOSITE REVERSE OSMOSIS MEMBRANE | Nitto Denko Corporation (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1806174-A1 | PROCESS FOR PRODUCING SEMIPERMEABLE COMPOSITE MEMBRANE | Nitto Denko Corporation (JP) | 2007-07-11 | — | — | EP | disclosed |