Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP3 | P08254 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900002 | 0.86 | MMP2 (0.46) | MMP13MMP2MMP3MAPTPOLB | |
| SCHEMBL7451339 | 0.78 | MMP2 (0.58) | MMP13MMP2MMP3MAPTPOLB | |
| SCHEMBL9661011 | 0.67 | MAPT (0.78) | MAPTPOLBPKMMEN1KMT2A | |
| SCHEMBL16774419 | 0.67 | KMT2A (0.59) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL7356599 | 0.66 | KMT2A (0.67) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL14544527 | 0.66 | ALDH1A1 (0.71) | MAPTPOLBPKMMEN1KMT2A | |
| SCHEMBL24534671 | 0.66 | MEN1 (0.74) | MAPTPOLBMEN1KMT2ALMNA | |
| SCHEMBL9811421 | 0.65 | ALDH1A1 (0.54) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL12891199 | 0.64 | POLB (0.60) | MMP13MMP2MAPTPOLBMEN1 | |
| Acetylsulfanilamide SCHEMBL17360801 | 0.64 | CA1 (0.86) | MEN1KMT2AALDH1A1L3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |