Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.46 |
| ▸ | MMP13 | P45452 | 6/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899545 | 0.86 | MMP13 (0.51) | MMP2MMP13MMP3CA1CA2 | |
| SCHEMBL7455660 | 0.75 | MMP13 (0.73) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7451384 | 0.75 | MMP2 (0.53) | MMP2MMP13MMP3CA1CA2 | |
| SCHEMBL7514640 | 0.70 | CA1 (0.44) | MMP2MMP13MMP3CA1CA2 | |
| SCHEMBL13588729 | 0.67 | CA1 (0.62) | MMP2MMP13CA1CA2CA12 | |
| SCHEMBL14411540 | 0.66 | CA1 (0.61) | MMP2MMP13CA1CA2CA12 | |
| SCHEMBL10602501 | 0.65 | CA1 (0.51) | MMP2MMP13CA1CA2CA12 | |
| SCHEMBL8009645 | 0.65 | CA1 (0.69) | MMP2MMP13CA1CA2CA12 | |
| SCHEMBL10088209 | 0.64 | ALDH1A1 (0.63) | MMP2MMP13CA1CA2CA12 | |
| SCHEMBL11883912 | 0.63 | POLB (0.69) | MMP2MMP13CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |