Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685687 | 1.00 | MAOB (0.49) | MAOBDDB1CRBNKCNH3F2 | |
| SCHEMBL7906013 | 1.00 | MAOB (0.49) | MAOBDDB1CRBNKCNH3F2 | |
| SCHEMBL2978224 | 0.89 | MAOB (0.46) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL291567 | 0.88 | HSD11B1 (0.47) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL5200672 | 0.82 | RECQL (0.44) | MAOB | |
| SCHEMBL9026480 | 0.82 | CYP26A1 (0.47) | — | |
| SCHEMBL11870917 | 0.82 | FASN (0.45) | KCNH3 | |
| SCHEMBL29173299 | 0.81 | MAOB (0.60) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL19540607 | 0.81 | MAOB (0.60) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL31708239 | 0.80 | ALDH1A1 (0.36) | MAOBKCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960750-A | Baeyer-Villiger monooxygenase, mutant and application thereof in preparation of chiral butyrolactone | 华东理工大学 | 2023-04-14 | — | — | CN | disclosed |
| US-6207862-B1 | PRECURSORS ARE CHIRAL 4-HYDROXYCARBOXAMIDES, 4-HYDROXYHYDROXAMIC ACIDS, OR 4-HYDROXYHYDRAZIDES PRODUCED FROM GAMMA-LACTONES, WHICH IN TURN ARE DERIVED FROM 1,4-DIOLS BY STEREOSELECTIVE OXIDATION, | BIOCATALYTICS, INC. | 2001-03-27 | — | — | US | disclosed |
| WO-1999032649-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL 1,3-AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| US-5916786-A | Method for the production of chiral 1,3-aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-06-29 | — | — | US | disclosed |