Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 6/20 | 0.47 |
| ▸ | ESR1 | P03372 | 7/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2693144 | 0.89 | ESR1 (0.49) | CYP26A1ESR1ESR2CAPN1CYP24A1 | |
| SCHEMBL5200672 | 0.83 | RECQL (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL3685687 | 0.82 | MAOB (0.49) | — | |
| SCHEMBL7906013 | 0.82 | MAOB (0.49) | — | |
| SCHEMBL7899581 | 0.82 | MAOB (0.49) | — | |
| SCHEMBL31708239 | 0.80 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9566869 | 0.79 | GLA (0.50) | CYP26A1CYP24A1CYP3A4 | |
| SCHEMBL5572711 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8163894 | 0.79 | P2RX7 (0.42) | — | |
| SCHEMBL30468832 | 0.79 | CYP19A1 (0.52) | CYP26A1ESR1ESR2CAPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719763-A1 | 4-(Quinolin-2-yl-methoxy)-phenyl acetic acid derivatives with antiatherosclerotic activity | BAYER AG (DE) | 1996-07-03 | — | — | EP | disclosed |