Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448626 | 0.93 | FAAH (0.53) | FAAHMEN1KMT2ALMNANPC1 | |
| SCHEMBL424617 | 0.90 | FAAH (0.48) | FAAHMEN1KMT2ALMNANPC1 | |
| SCHEMBL427524 | 0.83 | HSD17B2 (0.46) | FAAHKMT2ALMNAHTTALDH1A1 | |
| SCHEMBL443278 | 0.74 | FAAH (0.54) | FAAHMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL425585 | 0.74 | FAAH (0.57) | FAAHMEN1KMT2ALMNANPC1 | |
| SCHEMBL27529994 | 0.74 | ALPL (0.45) | FAAHMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14950181 | 0.73 | DRD2 (0.50) | FAAHSMN1; SMN2 | |
| SCHEMBL14950285 | 0.73 | CNR2 (0.54) | LMNAHTTCNR1TSHR | |
| SCHEMBL427826 | 0.72 | FAAH (0.49) | FAAHMEN1KMT2ALMNAHTT | |
| SCHEMBL14950180 | 0.70 | MAPT (0.48) | FAAHNPC1TDP1SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |