Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966915 | 0.92 | CA9 (0.54) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL28223385 | 0.84 | KMT2A (0.75) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL5445981 | 0.84 | KMT2A (0.75) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL10667599 | 0.84 | KMT2A (0.75) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL5447975 | 0.84 | KMT2A (0.75) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL5446742 | 0.84 | KMT2A (0.75) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL5445779 | 0.84 | KMT2A (0.75) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL11068116 | 0.84 | KMT2A (0.75) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL8438232 | 0.83 | LMNA (0.65) | LMNASMN1; SMN2KMT2AHTTMEN1 | |
| SCHEMBL8443237 | 0.83 | LMNA (0.65) | LMNASMN1; SMN2KMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197797-B1 | ANTICANCER AGENTS; SKIN DISORDERS | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-03-06 | — | — | US | disclosed |
| EP-0984939-A1 | CYANOGUANIDINES AS CELL PROLIFERATION INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054145-A1 | CYANOGUANIDINES AS CELL PROLIFERATION INHIBITORS | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-12-03 | — | — | WO | disclosed |