Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | QPCT | Q16769 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900117 | 0.92 | LMNA (0.59) | KMT2ALMNASMN1; SMN2ALDH1A1QPCT | |
| SCHEMBL8915063 | 0.88 | CA9 (0.58) | CA9HRH2KMT2ALMNAALDH1A1 | |
| SCHEMBL7901763 | 0.87 | KMT2A (0.71) | CA9HRH2KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7904143 | 0.87 | KMT2A (0.71) | CA9HRH2KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8915308 | 0.86 | CA9 (0.60) | CA9HRH2KMT2ALMNAALDH1A1 | |
| SCHEMBL11839390 | 0.85 | CDK1 (0.63) | CA9KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8917236 | 0.84 | L3MBTL1 (0.56) | CA9HRH2KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8916496 | 0.84 | L3MBTL1 (0.56) | CA9HRH2KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8916068 | 0.84 | L3MBTL1 (0.56) | CA9HRH2KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8916892 | 0.84 | L3MBTL1 (0.56) | CA9HRH2KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300345-B1 | AS ANTIPROLIFERATIVE AGENT | Leo Pharmacuetical Products Ltd. A/S (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-10-09 | — | — | US | disclosed |