SCHEMBL7900324

SCHEMBL7900324

C=C(CC(CC)=C(C=CC(=O)O)C(=O)O)C(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.36
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906062 0.85 HCAR2 (0.36) HCAR2ALDH1A1ALOX15HSD17B10
SCHEMBL7900779 0.80 ALDH1A1 (0.33) ALDH1A1
SCHEMBL8901060 0.75 HCAR2 (0.33) HCAR2
Maleic Acid SCHEMBL28189741 0.74 HCAR2 (0.45) HCAR2ALDH1A1ALOX15HSD17B10
SCHEMBL6244209 0.72 HCAR2 (0.39) HCAR2ALDH1A1ALOX15HSD17B10
Monomethyl Fumarate SCHEMBL8952278 0.70 HCAR2 (0.61) HCAR2ALDH1A1ALOX15HSD17B10
SCHEMBL7059943 0.70 ALOX15 (0.34) HCAR2ALDH1A1ALOX15HSD17B10
Acrylic Acid SCHEMBL27967337 0.69 ALOX15 (0.47) HCAR2ALDH1A1ALOX15HSD17B10
Maleic Acid SCHEMBL3692041 0.68 HCAR2 (0.45) HCAR2ALDH1A1ALOX15HSD17B10
Fumaric Acid SCHEMBL7520083 0.67 TSHR (0.45) HCAR2ALDH1A1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4230654-A COATING OF MACROMOLECULAR COMPOUND UNITIKA LIMITED (JP) 1980-10-28 US claimed
US-6197409-B1 Ink-jet media E. I. DU PONT DE NEMOURS AND COMPANY 2001-03-06 US disclosed
US-5984467-A Ink-jet media E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-16 US disclosed
EP-0782931-B1 Receptor sheet for recording by ink-jet DU PONT (US) 1999-10-13 EP disclosed
EP-0672538-B1 Reactive media-ink system for ink jet printing DU PONT (US) 1998-09-02 EP disclosed
EP-0782931-A1 Receptor sheet for recording by ink-jet E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-07-09 EP disclosed
US-5537137-A PRINTING INK JET INK ON SUPPORT BEARING INK RECEIVING COATING CONTAINING HYDROPHILIC POLYMERIC BINDER AND REACTIVE COMPONENT, EXPOSING TO ENERGY SOURCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-16 US disclosed
EP-0672538-A1 Reactive media-ink system for ink jet printing E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-20 EP disclosed
US-5429860-A Durability; coating is blend of hydrophilic polymer and active material E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-04 US disclosed