Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9890972 | 0.87 | HTR6 (0.35) | HTR6TP53ALDH1A1KDM4EHPGD | |
| SCHEMBL13074830 | 0.83 | HTR6 (0.39) | HTR6TP53RXFP1ADORA1ALDH1A1 | |
| SCHEMBL15433731 | 0.81 | BRD4 (0.42) | HTR6TP53RXFP1ALDH1A1KDM4E | |
| SCHEMBL7906965 | 0.79 | KDM4E (0.39) | HTR6TP53RXFP1ADORA1ALDH1A1 | |
| SCHEMBL7909713 | 0.79 | HTR6 (0.37) | HTR6TP53RXFP1ALDH1A1KDM4E | |
| SCHEMBL7909715 | 0.77 | HTR6 (0.39) | HTR6TP53RXFP1ALDH1A1KDM4E | |
| SCHEMBL7906969 | 0.76 | KDM4E (0.42) | HTR6TP53RXFP1ALDH1A1KDM4E | |
| SCHEMBL13074827 | 0.76 | HPGDS (0.44) | HTR6TP53RXFP1KDM4ENPSR1 | |
| SCHEMBL13074829 | 0.76 | HTR6 (0.38) | HTR6TP53RXFP1ALDH1A1KDM4E | |
| SCHEMBL13074562 | 0.72 | TP53 (0.39) | HTR6TP53RXFP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107965-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | WO | disclosed |