Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789036 | 0.91 | GFER (0.34) | PROKR1KMT2ASIRT2DPP4CFD | |
| SCHEMBL2789039 | 0.91 | GFER (0.34) | PROKR1KMT2ASIRT2DPP4CFD | |
| SCHEMBL2818273 | 0.90 | PROKR1 (0.43) | PROKR1MMP13NPC1RAB9AKMT2A | |
| SCHEMBL2789223 | 0.89 | ALDH1A1 (0.33) | PROKR1NPC1RAB9AKMT2ADPP4 | |
| SCHEMBL2789221 | 0.89 | ALDH1A1 (0.33) | PROKR1NPC1RAB9AKMT2ADPP4 | |
| SCHEMBL2790247 | 0.89 | PROKR1 (0.35) | PROKR1MMP13NPC1RAB9AKMT2A | |
| SCHEMBL7894446 | 0.89 | PROKR1 (0.35) | PROKR1MMP13NPC1RAB9AKMT2A | |
| SCHEMBL2790244 | 0.89 | PROKR1 (0.35) | PROKR1MMP13NPC1RAB9AKMT2A | |
| SCHEMBL2790088 | 0.88 | DPP4 (0.32) | PROKR1KMT2ADPP4CFDKCNH2 | |
| SCHEMBL2792284 | 0.88 | DPP4 (0.32) | PROKR1KMT2ADPP4CFDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |