Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277150 | 0.74 | ADRA1D (0.61) | ADRA1AADRA1DADRA1BCYP3A4LMNA | |
| SCHEMBL2321445 | 0.70 | ADRA1D (0.81) | ADRA1AADRA1DADRA1BLMNAGAA | |
| SCHEMBL6692977 | 0.69 | OPRD1 (0.41) | ADRA1AADRA1DADRA1BCYP3A4LMNA | |
| SCHEMBL327601 | 0.69 | OPRD1 (0.41) | ADRA1AADRA1DADRA1BCYP3A4LMNA | |
| SCHEMBL545962 | 0.69 | ADRA1A (0.39) | ADRA1AADRA1DADRA1BCYP3A4LMNA | |
| SCHEMBL290880 | 0.69 | — | — | |
| SCHEMBL3970107 | 0.69 | OPRD1 (0.41) | ADRA1AADRA1DADRA1BCYP3A4LMNA | |
| Bromide SCHEMBL7969410 | 0.67 | OPRD1 (0.40) | ADRA1AADRA1DADRA1BCYP3A4LMNA | |
| SCHEMBL21084974 | 0.66 | NPC1 (0.32) | ADRA1AADRA1DADRA1BOPRD1 | |
| Azapetine SCHEMBL456796 | 0.66 | ADRA1D (1.00) | ADRA1AADRA1DADRA1BLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184302-B1 | RETENTION AIDS AND/OR FIXING AGENTS IN PAPERMAKING | CLARIANT CORPORATION (DE) | 2001-02-06 | — | — | US | disclosed |
| US-5973108-A | Unsaturated polycations and their preparation and use | CLARIANT GMBH (DE) | 1999-10-26 | — | — | US | disclosed |