SCHEMBL7900738

SCHEMBL7900738

COC(=O)c1ccc(OCc2ccccc2)cc1OC(C)c1ccccc1C

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.46
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910697 0.90 MCL1 (0.50) MAOBLMNAL3MBTL1
SCHEMBL7914674 0.88 MAOB (0.47) MAOBLMNAL3MBTL1
SCHEMBL7900742 0.86 ALDH1A1 (0.45) MAOB
SCHEMBL3181500 0.85 MAOB (0.56) MAOBLMNAL3MBTL1HPGD
SCHEMBL3962253 0.83 MAOB (0.61) MAOBLMNAHPGD
SCHEMBL3201763 0.81 MAOB (0.57) MAOBLMNAHPGD
SCHEMBL4277112 0.81 MAOB (0.53) MAOBLMNAHPGD
SCHEMBL3191667 0.80 MAOB (0.58) MAOBLMNAL3MBTL1HPGD
SCHEMBL21924287 0.80 MAOB (0.58) MAOBLMNAHPGD
SCHEMBL1763456 0.79 MAOB (0.57) MAOBLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211234-B1 BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID RHONE-POULENC RORER LIMITED (GB) 2001-04-03 US disclosed
EP-0728128-B1 SUBSTITUTED PHENYL COMPOUNDS RHONE POULENC RORER LTD (GB) 1998-09-16 EP disclosed
EP-0728128-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1996-08-28 EP disclosed
WO-1995013262-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1995-05-18 WO disclosed