SCHEMBL7910697

SCHEMBL7910697

Cc1ccccc1C(C)Oc1cc(OCc2ccccc2)ccc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.50
MAOB P27338 1/20 0.49
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914674 0.91 MAOB (0.47) MCL1MAOBLMNAL3MBTL1
SCHEMBL7900738 0.90 MAOB (0.46) MAOBLMNAL3MBTL1
SCHEMBL7900742 0.87 ALDH1A1 (0.45) MAOB
SCHEMBL712875 0.84 MAOB (0.60) MCL1MAOBLMNAL3MBTL1
SCHEMBL7908997 0.81 MAOB (0.53) MCL1MAOBLMNAL3MBTL1
SCHEMBL7908633 0.80
SCHEMBL4756552 0.80 MAOB (0.63) MCL1MAOBLMNA
SCHEMBL7907463 0.79 MAOB (0.57) MCL1MAOB
SCHEMBL7907979 0.78
SCHEMBL1448026 0.78 MAOB (0.61) MCL1MAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211234-B1 BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID RHONE-POULENC RORER LIMITED (GB) 2001-04-03 US disclosed
EP-0728128-B1 SUBSTITUTED PHENYL COMPOUNDS RHONE POULENC RORER LTD (GB) 1998-09-16 EP disclosed
EP-0728128-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1996-08-28 EP disclosed
WO-1995013262-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1995-05-18 WO disclosed