SCHEMBL7900827

SCHEMBL7900827

CP(=S)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
ESR2 Q92731 1/20 0.46
HTT P42858 1/20 0.41
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 8/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
ACHE P22303 1/20 0.35
CFTR P13569 1/20 0.35
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10523176 0.85 ESR1 (0.41) ESR1ESR2HTTLMNANPSR1
SCHEMBL10521146 0.85 TSHR (0.43) ESR1ESR2HTTLMNANPSR1
SCHEMBL11890105 0.83 HTT (0.45) ESR1ESR2HTTLMNAL3MBTL1
SCHEMBL8933600 0.82 CA4 (0.52) HTTCA2CA4NPSR1L3MBTL1
SCHEMBL7200128 0.81 ESR1 (0.46) ESR1ESR2HTTCA2CA4
SCHEMBL19726389 0.80 KCNA5 (0.43) ALDH1A1CFTRSMN1; SMN2
SCHEMBL3790937 0.78 ACHE (0.38) ESR1ESR2HTTCA2LMNA
SCHEMBL21557205 0.77 ESR1 (0.42) ESR1ESR2HTTCA2CA4
SCHEMBL19732116 0.77 ESR1 (0.42) ESR1ESR2HTTCA2CA4
SCHEMBL8630054 0.77 ESR1 (0.42) ESR1ESR2HTTCA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772888-A Modified core-shell zinc-based nano-sheet and preparation method thereof 利亚德光电股份有限公司 2024-10-15 CN claimed
WO-2024021189-A1 METHOD FOR PREPARING ORGANIC PHOSPHORUS COMPOUND BY HIGH-SELECTIVITY REDUCTION OF PHOSPHORUS SULFUR COMPOUND 浙江扬帆新材料股份有限公司 2024-02-01 WO claimed
CN-116022740-A Anhydrous Na 2 S and preparation method of derivative thereof 浙江扬帆新材料股份有限公司 2023-04-28 CN claimed
US-11072696-B2 Nitrile group-containing copolymer rubber and nitrile group-containing copolymer rubber cross-linked product ZEON CORPORATION (JP) 2021-07-27 US claimed
CN-119684360-A Method for preparing organic phosphine compound by hydrogen high-selectivity reduction of phosphine sulfur compound 浙江扬帆新材料股份有限公司 2025-03-25 CN disclosed
CN-118772888-A Modified core-shell zinc-based nano-sheet and preparation method thereof 利亚德光电股份有限公司 2024-10-15 CN disclosed
CN-117510541-A Method for purifying phosphino compound 浙江扬帆新材料股份有限公司 2024-02-06 CN disclosed
CN-116022740-A Anhydrous Na 2 S and preparation method of derivative thereof 浙江扬帆新材料股份有限公司 2023-04-28 CN disclosed
CN-115490727-A Method for preparing organic phosphine compound by high-selectivity reduction of phosphine sulfur compound 浙江扬帆新材料股份有限公司 2022-12-20 CN disclosed
CN-110352217-B Nitrile group-containing copolymer rubber and crosslinked nitrile group-containing copolymer rubber 日本瑞翁株式会社 2022-03-08 CN disclosed
US-20210355378-A9 HETEROCYCLIC COMPOUNDS EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) AND THEIR USE IN ELECTROLUMINESCENT DEVICES UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2021-11-18 US disclosed
US-11072696-B2 Nitrile group-containing copolymer rubber and nitrile group-containing copolymer rubber cross-linked product ZEON CORPORATION (JP) 2021-07-27 US disclosed
US-20110196053-A1 HALOGEN-FREE, PHOSPHORUS-CONTAINING FLAME-RETARDANT POLYMER FOAMS BASF SE (DE) 2011-08-11 US disclosed
US-6331628-B1 REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed
US-6288268-B1 REACTION OF OLEFIN WITH ALCOHOL, OXYGEN AND CARBON MONOXIDE IN THE PRESENCE OF CATALYST FOR BISALKOXYCARBONYLATION WITH NOBLE MEYAL AND PHOSPHINE CHALCOGENIDE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-09-11 US disclosed
US-6184390-B1 Catalyst for bisalkoxycarbonylation of olefins, and method for production of succinate derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-02-06 US disclosed
US-6159891-A Catalyst for bisalkoxycarbonylation of olefins, and method for production of succinate derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-12-12 US disclosed
US-4873360-A Process for the preparation of cyclopentanoids and novel intermediates produced thereby BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1989-10-10 US disclosed
US-4806691-A Process for the preparation of tertiary phosphine oxides HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-21 US disclosed
US-4675446-A OXIDATION OF PHOSPHINE SULFIDES HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355378-A9 HETEROCYCLIC COMPOUNDS EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) AND THEIR USE IN ELECTROLUMINESCENT DEVICES ETFA, TEAD2, TERF2 ESR1 1541/4885ESR2 2385/4885HTT 823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.